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It is long known that cobalamin binds thiols through a strong and stable interaction of the formal cobalt(III) center with the thiolate anion of several biothiols such as glutathione [66]

A primary concern is the lack of selectivity among current DYRK1A inhibitors (Chen et al

Updated March 5, 2025

Complete treatment benefits typically become apparent following three to six months of consistent therapy, with most patients achieving substantial outcomes

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17, that IV glutathione, despite its skin-whitening effects, poses serious health risks, including potential kidney damage and even fatal consequences