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Side Effects and Safety Monitoring The most common adverse effects in clinical trials were gastrointestinal: nausea (15.8%, 20.3%), diarrhea (8.5%, 8.8%), and vomiting (5.0%, 9.2%) [1]

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Prior authorization is required by most insurance plans, meaning your doctor must submit documentation proving medical necessity before coverage is approved

If you're of childbearing potential, discuss family planning with your provider, as semaglutide should generally be discontinued at least 2 months before a planned pregnancy according to FDA guidance

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All the doses of semaglutide reduced HbA1c and body weight in both trial product estimand and treatment policy estimand, but clinically significant reduction was reported by the 14 mg dose