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[6] In all cases, a healthcare provider should evaluate patient history for any contraindication before initiating therapy

Pernicious anaemia is caused by your immune system preventing your stomach and gut from absorbing B12 from your food

But with appropriate treatment, the prognosis is excellent

Not having enough Vitamin B12 can cause a lot of problems, including abnormally large red blood cells (macrocytosis), anemia (pernicious anemia and macrocytic anemia), and in severe cases, psychosis and death

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The vitamin plays a role in producing neurotransmitters like serotonin, which regulate mood