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Platelet-rich fibrin (PRF) is a second-generation platelet concentrate that forms a fibrin matrix enriched with platelets, leukocytes, and growth factors, and promotes sustained tissue regeneration without the need for anticoagulants [6]

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Since hyperinsulinemia is a primary driver of excess ovarian androgen production in PCOS, improving insulin sensitivity can lower testosterone through a mechanism that is independent of weight loss alone