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The applicant also noted that only the aprevo insertion instrumentation, cleared by FDA, is authorized to implant the aprevo Cervical interbody device, and these instruments are not available to be purchased separately for use with other devices

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Despite the lack of clear evidence in humans, the UKs Medicines and Healthcare products Regulatory Agency (MHRA) and manufacturers maintain a cautious stance

Patients who push training frequency and intensity are limited not by motivation but by connective tissue recovery

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