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Spirulina can be added as a third layer for its prebiotic-like effects on beneficial gut bacteria

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2.8.2 Clinical studies Increased accumulation of iron in substantia nigra of PD patients was observed with MRI techniques in post mortem studies with significant accumulation in putamen, red nucleus, nucleus caudatus and globus pallidus (Wang et al., 2016) and similar imaging findings on nigrosome imaging were found in cases of PD and parkinsonian syndromes (Li et al., 2022)