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Wellness circles have discussed its potential role in promoting gut lining integrity, especially in individuals affected by high stress, poor diet, or lifestyle imbalances

- It supports continuity of care

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Human evidence remains limited and does not establish BPC-157 as clinically proven

However, the requirement for HSL phosphorylation has recently been challenged as studies by the Granneman group elegantly show that direct activation of PNPLA2 in the absence of PKA stimulation is sensitive to HSL inhibition, suggesting that PNPLA2-mediated generation of DAG is sufficient to promote HSL activity (49)