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MT-2 is non-selective and produces tanning, sexual, and appetite effects

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Nausea and vomiting were reported three times more frequently with agents like semaglutide, dulaglutide, liraglutide, and tirzepatide than with placebo

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The authors noted that these cases raise important questions about the medications post-marketing safety profile, particularly regarding effects that may not have been captured in the controlled trial environment