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Injection-site reactions are among the most commonly reported side effects: patients may experience pain, stinging, or mild burning at the IM injection site

This glucose-dependence is the reason why GLP-1 agonists rarely cause hypoglycaemia in monotherapy unlike sulfonylureas which stimulate insulin secretion regardless of glucose level Glucagon suppression: Semaglutide suppresses glucagon secretion from pancreatic alpha cells also in a glucose-dependent manner

Could this disrupt formulary strategies, forcing employers to rethink plan designs

Kruglikov I, Wollina U

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