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Severe dehydration, otherwise known as the Hangover Cure 2

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The popularity of coffee enemas declined during the 20th century and their citation as a folk medical practice was removed from the best-selling textbook Merck Manual in 1972

It is best suited for intravenous procedures because the concentration of electrolytes and water is equal to that in serum plasma (0.9%)

The medication works by mimicking the incretin hormone GLP-1, which stimulates insulin secretion, suppresses glucagon release, and slows gastric emptying

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