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Consequently, antioxidants play a crucial role, either by scavenging ROS and RNS [14,15] or by modulating redox signaling pathways [16]
Studies utilizing genetic knockdowns or pharmacological inhibitors have shown that disruption of one antioxidant system often leads to compensatory upregulation and increased reliance on the other, underscoring their functional interdependence [45]
Chem Res Toxicol (2015) 28(10):19919
Thabet NM, Abdel-Rafei MK, Amin MM (2023) Fractionated whole body -irradiation aggravates arthritic severity via boosting NLRP3 and RANKL expression in adjuvant-induced arthritis model: the mitigative potential of ebselen
This unique amino acid derivative is also notable for its ability to cross the blood-brain barrier, which is why some individuals choose it as part of their wellness routines to support both physical and mental performance
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