CIPN occurs in up to 80% of cancer patients receiving cytotoxic chemotherapeutic agents, in which the class of antineoplastic agents, therapeutic dose and duration affect the severity and pathophysiology of the disease [2, 3]
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However, these RNAi-based interventions are in a preliminary stage, and exhaustive research is required to clarify the therapeutic benefits and safety of these innovative approaches before their clinical application 20
Potent mimics The active ingredient in Novo Nordisks Ozempic and Wegovy is semaglutide, which formally belongs to a group of drugs known as glucagon-like peptide 1 receptor agonists, or GLP-1RAs for short
Here are the public health implications for these new research findings
Based on the association of MASH with diabetes and obesity, researchers are evaluating GLP-1s as a potential treatment option for MASH