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Effect of host derived glutathione on disease susceptibility of host cells to Frog Virus 3 To explore whether changes in host cell glutathione cause a generalised effect on disease susceptibility, the above experiment was repeated with a ranavirus as an alternative amphibian pathogen

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This study not only elucidates the mechanisms of PARP1-mediated PXR E194 ribosylation in AILI but also identifies Sch B as the first specific inhibitor of this pathway, providing a theoretical basis for precision detoxification strategies targeting posttranslational modifications

Two Cases of Refractory Cardiogenic Shock Secondary to Bupropion Successfully Treated with Veno-Arterial Extracorporeal Membrane Oxygenation