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In summary, the highly reactive primary products (L-OOHs) and secondary products (e.g., MDA and 4-HNE) generated during lipid peroxidation are toxic molecules that cause cell damage ( 2.2 Iron overload Iron metabolism refers to the processes of absorption, transport, distribution, storage, utilization, transformation, and excretion of iron within an organism (Roemhild et al., 2021)

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While this application requires further clinical investigation, some studies have shown the peptide stimulating cartilage cell proliferation and demonstrating potential benefits for osteoarthritis treatment

Mitochondrial structure monitoring by transmission electron microscope (TEM) is crucial for determining the occurrence of ferroptosis in the cells (Stockwell et al., 2017)

The process dissolves the freeze-dried powder into a liquid solution that can be drawn into a syringe and administered

[DOI] [PMC free article] [PubMed] [Google Scholar] Eastmond PJ