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Competition will depend on efficacy, dosing, tolerability, supply, price, and indication breadth

Omalizumab in Patients With Severe Asthma and Persistent Sputum Eosinophilia

Elevated MMA levels in patients with vitamin B12 deficiency can contribute to myelin damage (myelopathy) and, consequently, peripheral and autonomic neuropathy ( Cobalamin deficiency can lead to neurological manifestations such as progressive axonal demyelination, impaired peripheral and sensory nerve function, areflexia, loss of proprioception and vibration sensitivity, and subacute combined spinal cord degeneration (70)

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583 Similarly, siZIP4 evoked an epithelioid phenotype in NSCLC, reduced the expression of CSC markers, and elevated cisplatin sensitivity

Matoori S, Leroux JC (2015) Recent advances in the treatment of hyperammonemia