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Beinaglutide showed significant weight-loss benefit and effective glycaemic control for the treatment of type 2 diabetes in a real-world setting: a 3-month, multicentre, observational, retrospective, open-label study

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It has long been known that growth differentiation factor 8 (GDF8, also known as myostatin), acting via the activin type II receptors ActRIIA/B in skeletal muscle, is a major negative regulator of muscle mass 7,8,9

Despite these challenges, participants on semaglutide 2.4 mg achieved an average weight loss of 9.64%, with significant improvements in glycemic control

95% CI, 0.77-0.96

"Some patients find that injecting in the evening helps reduce nausea," she says, noting that light carbohydrates like crackers can help settle the stomach