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It has been studied extensively for immune modulation across various conditions, from hepatitis B and C to cancer immunotherapy to vaccine enhancement in elderly populations

A second comparison is with the N-terminal copper-binding site of human serum albumin, which uses the sequence Asp-Ala-His-Lys (DAHK) at the N-terminus of the albumin protein to bind copper(II) through the same general N-terminal/histidine/amide-nitrogen coordination geometry

[DOI] [PubMed] [Google Scholar] 40.Elewski B, Rich P, Lain E, Soung J, Lewitt GM, Jacobson A