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When it modulates brain signaling, you simply want less food

doi: 10.1038/s41586-022-05089-y

One of the most significant of these is the activation of SIRT1, often called a longevity gene. SIRT1 helps manage insulin sensitivity and supports healthier blood sugar regulation, which is fundamental for sustained energy and preventing the metabolic strain that can lead to weight gain

The EAT-lancet diet in relation nutrient intake among older adults: insights from the Gothenburg H70 birth cohort study

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