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doi: 10.3390/nu12061562 35 AlshammariMKFatimaWAlrayaRAAlzahraniAKKamalMAlshammariRSet al

Emerging data suggest potential benefit in Parkinsons disease, Alzheimers disease, multiple sclerosis, and acute brain injury

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Furthermore, the transcription factor NFE2 like bZIP transcription factor 2 (NFE2L2, best known as NRF2) is a pivotal regulator of the antioxidant system and controls the expression of genes central to antioxidant defense mechanisms [28]

Urata Y, Ihara Y, Murata H, Goto S, Koji T, Yodoi J et al (2006) 17Beta-estradiol protects against oxidative stress-induced cell death through the glutathione/glutaredoxin-dependent redox regulation of Akt in myocardiac H9c2 cells