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Some individuals may feel mild digestive discomfort if they start with a high dose

Dysregulation of the HPA axis and elevated pro-inflammatory cytokine levels may impair neurogenesis in the hippocampus, reduce neural plasticity in the prefrontal cortex, and contribute to the onset and persistence of PSD (Koo et al., 2010)

Clinicians across multiple specialties

Ferris: Unfortunately, what we know about stopping the drug is that those hunger signals tend to come back

The side effect profiles differ between semaglutide and tirzepatide , so switching medications is sometimes the solution

PPT, Personalized Postprandial Glucose-Targeting