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Amphetamine enters presynaptic neurons by passive diffusion and through plasma membrane monoamine transporters, including the dopamine transporter (DAT) in dopaminergic neurons, the norepinephrine transporter (NET) in adrenergic neurons, and the serotonin transporter (SERT) in serotinergic neurons

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Dosage can be gradually increased as tolerated to achieve the desired effects

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