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A multicenter, 16-week, double-blind, placebo-controlled study in children and adolescents with PWS and obesity found that liraglutide had no impact on BMI in children or adolescents after 16 weeks of treatment, nor was weight improved after 52 weeks on the drug compared to placebo

Molecular structure: Semaglutide has a 94% sequence homology with human GLP-1 but includes modifications that enhance stability and binding affinity to the GLP-1 receptor

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This weakened response to GLP-1 can make it challenging to manage blood sugar levels in patients with diabetes and may require alternative treatment methods or adjustments in medication dosage. Medication interference People taking a GLP-1 drug with other medications may see less weight loss

Therapeutic Efects: Pancreas: Promotes glucose-dependent insulin secretion and protects -cells

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