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The effectiveness of compound X is oftentimes dependent on the presence of compounds Y and Z and so on
PLoS ONE 14 , e0216143 (2019)
Within the context of PCOS, GPER not only influences the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) by regulating the function of the hypothalamicpituitaryovarian (HPO) axis but also improves ovarian function, reduces androgen levels, and promotes normal follicular development and ovulation [156]
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