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Supplementation with riboflavin was reported to temporarily slow the disease progression in a patient with the severe encephalomyopathy [155]

Prolonged or unprotected sun exposure signals melanocytes to produce more pigment as a defense mechanism, resulting in tanning and sun-induced hyperpigmentation

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The inhibition of the onset and progression of DKD is an urgent issue, and the development of therapeutic approaches against DKD is required