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[8] Although not an absolute contraindication, patients with coronary artery disease or unstable angina should only use B-Complex injections containing niacinamide under physician supervision, since high-dose niacin supplements have been linked to arrhythmias in such patients
Improved Functional Outcomes (Short-term): Patients who received ESIs reported more successful outcomes compared to those receiving conservative treatment in terms of successful events (defined by pain reduction), particularly in the short-to-intermediate term
Are Vitamin B12 Injections Safe
Endocrinology, 142(12), 51825189
Additionally, lifestyle factors like diet and exercise can influence the longevity of the shots effects