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Previous studies have shown that the mechanism by which chemotherapy drugs induce tumor cell death primarily involves the promotion of ROS production [14]

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Under normal conditions, antioxidant systems neutralize ROS

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Artificial organelles (Uri/Cat@ArtPC) leverage -polylysine/DNA phase separation to co-encapsulate uricase and catalase, enabling synergistic urate conversion and H 2 O 2 neutralization, with enhanced renal targeting and catalytic durability (Hu H