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To much production of oxidants results into oxidative damage to cells and matrix molecules in the gingival tissues, like lipid peroxidation, protein oxidation, and DNA damage, aggravating the severity and duration of the inflammatory response ( 2.3 Role of oxidative stress in the pathogenesis of periodontitis In the pathogenesis of periodontitis, oxidative stress is of great importance

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De Putter, L

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(136) published research in 2022 demonstrating that DKD progression in T2DM patients is associated with impaired amino acid metabolism