All research referenced in this article was conducted in animal models or in vitro systems
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The study also showed significant reductions compared to other diabetes medications, including older generation GLP-1RAs
Acute dosing studies show immediate enzyme inhibition, but chronic metabolic remodelling follows a slower timeline that matches adipocyte turnover rates
10.1161/CIRCRESAHA.116.305372 [DOI] [PMC free article] [PubMed] [Google Scholar] 142.Ranek MJ, Bhuiyan MS, Wang X