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This is also the period where non-responders become apparent

These studies often employ daily or twice-daily dosing regimens for periods spanning days to weeks, depending on the condition under investigation, such as tissue repair or gastrointestinal healing

tissue distribution

Enzymatic antioxidants are superoxide dismutase (SOD), catalase, and glutathione peroxidase (GPx), and nonenzymatic antioxidants are vitamin E, vitamin C, vitamin A, selenium (Se), transferrin, and lactoferrin

Consensus statements 2.1.1 The prevalence of concurrent extrahepatic autoimmune disorders in pediatric autoimmune liver disease varies between 21 and 48%