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Key Takeaways Section 3 The FTCs 1990s divestiture orders addressed manufacturer-PBM co-ownership but left insurer-PBM vertical integration largely unchallenged for two decades

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In the new substudy, once weekly semaglutide (1 mg) was shown to reduce the risk of time to first composite HF event (new onset or worsening HF leading to unscheduled hospital admission or urgent visit, with initiation of or intensified diuretic/vasoactive therapy) or cardiovascular death and HF events and cardiovascular death alone

3 That study didnt report why 50% of diabetics on GLP-1 RAs discontinued them, but gastrointestinal (GI) adverse events were a suggested cause

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Look AHEAD (Action for Health in Diabetes): design and methods for a clinical trial of weight loss for the prevention of cardiovascular disease in type 2 diabetes