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This review highlights that NAD+ levels decline with age and play a critical role in metabolic and cellular health, with supplementation shown to raise NAD+ levels and potentially combat aspects of age-related decline

These are cell and tissue culture findings, not human clinical outcomes, so they don't directly translate to what a person using a topical serum would experience

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High doses of vitamin B12 have been associated with acne breakouts (mainly from the injectable form, not the supplement), but also negative effects in people with diabetes and kidney problems

"Multifunctionality and Possible Medical Application of the BPC 157 Peptide: Literature and Patent Review." Pharmaceuticals , 2025

Studies suggest that AHK-Cu peptide may help promote the appearance of thicker, fuller-looking hair (when applied at clinical concentrations over time)