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After cells differentiate into mDA neurons, transforming growth factor-3 (TGF-3), GDNF, brain-derived neurotrophic factor (BDNF), and other factors maintain their survival (Yeap et al., 2023)

The individual amino acids are absorbed and can be used to resynthesize glutathione intracellularly, but this is a slow, rate-limited process that does not produce the acute plasma elevation seen with parenteral routes

To help reduce any gastrointestinal side effects, your physician will increase your dose gradually over the course of 16 to 20 weeks

[1] [3] The medication follows a dose-escalation schedule, gradually increasing to a maintenance dose of 2.4 mg

Endocr Rev 46(4):479500

The pay-as-you-go model resonates with patients who want control over their healthcare spending