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In pancreatic -cells (RINm5F), curcumin prevents desipramine (which belongs to TCAs) induced apoptosis by inhibiting the PI3K/AKT/FOXO1 pathway and disrupting AKAP150/PKA/PP2B interactions

Your diet: Vegans might benefit more from cyanocobalamin due to its potential for maintaining B12 levels

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They also show antioxidant and anti-inflammatory properties, supporting protection against oxidative stress

NHS Guidelines on B12 Treatment and Weight Management The NHS follows NICE and British Society for Haematology guidelines for B12 deficiency management, which emphasise evidence-based diagnosis and treatment protocols