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A fascinating study comparing lean and metabolically-challenged subjects found differential effects of butyrate supplementation
Gelhorn HL, Poon JL, Davies EW, et al
Hepatoprotective Effect of BPC 157, a 15-Amino Acid Peptide, on Liver Lesions Induced by Either Restraint Stress or Bile Duct and Hepatic Artery Ligation or CCl4 Administration
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Both approaches significantly lowered HbA1c levels (weighted mean difference [WMD] 0.75%, 95% CI 0.97 to 0.53) but increased hypoglycemic risk [risk ratio (RR) 7.59, 95% CI 3.3517.17] compared to the unchanged GLP-1RA