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Who Is a Safe Candidate and How to Evaluate Your Readiness Safe candidates for semaglutide after thyroidectomy typically have stable thyroid hormone replacement, normal baseline kidney function, and no history of medullary thyroid cancer or personal/family history of multiple endocrine neoplasia type 2

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All included studies reported baseline hormone values and used validated measurement techniques

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Compounded formulations permit rapid dosing customization and may align with patients who benefit from stepwise, microdefocused escalationparticularly relevant when genetic predisposition testing suggests variable GLP-1 receptor sensitivity