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Activation of gastrointestinal ileal brake response with dietary slowly digestible carbohydrates, with no observed effect on subjective appetite, in an acute randomized, double-blind, crossover trial

Vitamin B12 injections can help a deficiency, but a person with an average B12 level can replete himself by not taking supplements and eating foods rich in B12

Some specific agents have subsequently been approved for chronic weight management

Adequate B-12 levels may help prevent mood swings, stress, and emotional eating, contributing to a more balanced approach to weight management

Additionally, 127 participants who were obese or overweight and also had type 2 diabetes were enrolled

However, some patients experience mild ongoing symptoms that are manageable and, in their view, an acceptable trade-off for sustained weight loss