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Scientists are looking for better options

Recent studies have shown that several mutations in RNA-binding proteins (RBPs) can also cause ALS

TB-500 (43 amino acids) TB-500, the synthetic analog of Thymosin Beta-4 (T4), is a 43-amino-acid peptide derived from the TMSB4X gene

What a Herxheimer Reaction Feels Like Patients experiencing a Herxheimer reaction may report: Increased fatigue Worsening brain fog Muscle or joint pain Flu-like symptoms Sleep disruption Dizziness or head pressure Mood shifts or anxiety These symptoms can resemble a flare-up or relapse, which adds to the confusion

Proteom Clin Appl 2007

We used inverse-probability-of-censoring weights to address differential follow-up, and stabilized censoring weights were well behaved (few extremes), which helps explain why the confidence intervals are not excessively wide