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BBB is a biological and physical barrier consisting of astrocytes, pericytes, and brain microvascular endothelial cells (BMECs) that maintains the dynamic between the peripheral circulation and the central nervous system (21)

IV delivery puts the vitamin directly into the blood

Researchers started working with peptides in the 1920s, and synthetic peptides have been used to treat diabetes ever since

A 2023 study found that vitamin B12 deficiency is associated with higher body weight and fat mass, according to Healthline

B12 anaemia means you either have fewer red blood cells, or there is a lower amount than normal of haemoglobin in each of your red blood cells

Clinical significance was not established consistently