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doi: 10.1093/infdis/jix168 4 IllouzTBiragynAIulitaMFFlores-AguilarLDierssenMDe TomaIet al

Switching to a lower maintenance dose, rather than stopping completely, is a common approach

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Heres a breakdown our team often uses to illustrate the point

A 2023 study found that combining GHK-Cu with low-molecular-weight hyaluronic acid synergistically upregulated collagen IV by more than 25-fold in fibroblast models and doubled expression in skin underscoring how topical peptides can maintain firmness and repair after systemic cycles ( Jiang et al., 2023, J Cosmet Dermatol )

It's an important data point, not necessarily an alarm bell