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26 In patients who do not respond to a TNF inhibitor or in whom this response wanes, there are observational data to suggest that a switch to another agent in the class can be successful

Stack interventions: prescription anti-nausea meds, ginger, peppermint, strategic injection timing, BRAT diet on worst days, cold foods, acupressure

These include: Hypoglycemia (low blood sugar) Acute pancreatitis (inflammation of the pancreas) Changes in vision (due to diabetic retinopathy) Gallbladder problems Kidney injury Severe stomach problems Allergic or hypersensitivity reaction If you need to have surgery while taking tirzepatide, inform your healthcare provider, as the medication increases the risk of aspiration during anesthesia or deep sedation

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Int J Neurosci (2003) 113:683701