This coordinated mechanism effectively suppresses neuronal lipid peroxidation, thereby improving cognitive outcomes ( 3.6 Resveratrol Resveratrol, a naturally occurring non-flavonoid polyphenolic stilbenoid found in plants such as grapes, peanuts, and mulberries, downregulates the expression and activity of phosphodiesterase 4D (PDE4D)
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Bakermans AJ, et al
This interaction may explain observed improvements in mood, reduced substance cravings, and changes in compulsive food-seeking behavior
doi: 10.1093/toxsci/kfad125 120
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