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[8] [9] Zepbound is intended as an adjunct to a reduced-calorie diet and increased physical activity, not as monotherapy

Scientific References Wegovy 0.25 mg, FlexTouch solution for injection in pre-filled pen - Summary of Product Characteristics (SmPC)

This gradual approach is intentional

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Various methods have been proposed to enable oral delivery of protein and peptide therapeutics, including coadministration of compounds that alter the physiology of the GI tract, drug modifications, and delivery of the drug via a carrier, which was reviewed by Wagner et al

However, in combination with certain diabetes medications that increase insulin production or promote insulin use, the risk of hypoglycemia may be higher