P. Sikiricet al., Stable Gastric Pentadecapeptide BPC 157, Roberts Stomach Cytoprotection/Adaptive Cytoprotection/Organoprotection, and Selyes Stress Coping Response: Progress, Achievements, and the Future, The Editorial Office of Gut and Liver, Mar. 2020. doi: 10.5009/gnl18490
Data sources Orforglipron ATTAIN-1 trial: Eli Lilly press release (August 2025) Tirzepatide SURMOUNT-1 trial: Eli Lilly published data Indirect comparison metaanalysis: Circulation (2024) GI adverse events metaanalyses: Endocrinology, Diabetes & Metabolism (2024) and Diabetes, Obesity and Metabolism (2023)
doi: 10.3390/diagnostics15050547 32 TsatsanisCBobjerJRastkhaniHDermitzakiEKatrinakiMMargiorisANet al
It also plays a wider role, and understanding its support for metabolic health helps you see it as more than a weight-loss shortcut
Holz GGT, Leech CA, Habener JF
Researchers have studied BPC-157 primarily in animal models, where it has shown potential to support tissue repair, reduce inflammation, and protect the gut lining
