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Beyond gastrointestinal comorbidities, IBS commonly coexists with conditions like pain syndromes, overactive bladder, migraines, visceral sensitivity, and psychiatric conditions

Remember these three critical principles: Start Conservative : Always begin with the beginner dose to assess tolerance

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The injection can be performed by a physician, or by a nurse or assistant under the [direct supervision] of the physician.

In addition, researchers investigate its effects on nitric oxide pathways, epithelial stability, and cytokine balance across different experimental models