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4.2 Oxidative stress mediates metabolic abnormalities in PCOS Oxidative stress is closely related to obesity, IR, and HA in PCOS, and the induced apoptosis of ovarian GCs leads to follicular atresia, which is one of the mechanisms of ovulation disorders in PCOS (150)

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Heraa Chaudhry, MD, is a board-certified family medicine physician with more than a decade of clinical experience, specializing in preventative medicine, womens health, and integrative wellness