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That decline is part of why GHK-Cu became a target for skin, hair, and wound-healing research

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Average age and BMI of the participants of the longitudinal studies were 59.8 8.3 years and 29.2 5.7 kg/m 2

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Further, while low tryptophan dietary intake is rare, CFS and autoimmune hypothyroidism may be associated with an increment in indeloamine-dioxygenase (IDO) expression, which would promote the tryptophan-kynurenine pathway that decreases serotonin synthesis

These findings highlight the potential of combination strategies to maximize metabolic benefits, warranting further investigation in clinical studies