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Between 7580% of circulating GH is the 22-KDa isoform, 510% is the 20-KDa isoform, and the remaining levels occur as dimers, oligomers, and various other isoforms (Baumann, 2012)

Uniquely, studies suggest that Ipamorelin mimics the natural pulsatile secretion of GH without significantly stimulating the release of adrenocorticotropic hormone (ACTH), cortisol, or prolactin

Tesamorelin , a stabilized GHRH analog , binds the GHRH receptor on pituitary somatotrophs to stimulate endogenous growth hormone release and elevate IGF-1

GH-Secretagogue Pentapeptide Novo Nordisk Originator Literature Reported Mechanisms (Literature) Reported GHSR-1a agonism Selective agonism of the growth-hormone-secretagogue receptor (GHSR-1a) Raun et al

Yatawara, C., Einfeld, S., Hickie, I

Lets take a look at how the body grows: Height growth happens when epiphyseal (growth) plates at the ends of long bones are still open