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A meta-analysis of 113 RCTs comprising 33,167 patients in the GLP-1 RA cohort and 26,683 in the comparator cohort revealed no significant elevation in pancreatitis or pancreatic cancer risk relative to control groups (Mantel-Haenszel odds ratio [MH-OR] of 0.93 and 0.94, respectively), but identified a notable increase in cholelithiasis risk (MH-OR, 1.30) [58]

My only complaint is that it is so long

Compare that to nausea with an ROR of about 4

This area often has adequate subcutaneous fatty tissue, making it ideal for Semaglutide administration

Mental health effects were not a primary endpoint in these studies, though adverse event reporting captured some psychiatric symptoms

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