NovelleMGNaranjo-MartnezBLpez-CnovasJLDaz-RuizA
US labeling advises discontinuation when pregnancy is recognized but does not specify a preconception timeframe
HbA1cGoals The United Kingdom Prospective Diabetes Study demonstrated that for every percentage point reduction in HbA1c, there was a 35% reduction in the risk of complications in patients with type 2 diabetes
Translating Preclinical Data to Human Potential The NHP-to-human pharmacokinetic scaling suggests ASC35 may achieve a 30-day half-life or longer in humans
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Patients who experience side effects, plateaus, or inadequate response on one medication can switch to another