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That finding led to further studies and eventually to the development of Contrave , a combination of bupropion and another medication called naltrexone, approved by the FDA for weight management

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Although originally developed for the treatment of metabolic diseases, GLP-1-based therapies are now recognized for their influence on the same brain systems mediating drug-seeking and reward, suggesting therapeutic potential beyond glycemic control

Aging Neurosci

JendleJNauckMAMatthewsDRFridAHermansenKDringMet al

These compounds could complement lifestyle changes like balanced diet and exercise for long-term results